Out of Patients with Matthew Zachary
Out of Patients with Matthew Zachary
Matthew Zachary is the healthcare policy love child of Jon Stewart, Howard Stern, Thomas Paine, Ralph Nader, and Jerry Seinfeld. He has 19 years of receipts to prove it. Editorially independent. Answerable to no one. What started as The Stupid Cancer Show in 2007 became Out of Patients. The first online health podcast in America, predating the medium itself. Zachary survived brain cancer at 21, built the young adult cancer movement from scratch, and spent two decades channeling patient rage into something the system never saw coming. Now he is marching into Washington. Out of Patients goes where the comfortable shows will not. Politics. Healthcare policy. Economics. Institutional accountability. Consumer protection. The forces shaping what 330 million Americans can access, afford, and survive. Battle-scarred patients. Exhausted caregivers. Rare insiders brave enough to name what is killing us. And the occasional elected official about to find out what an organized patient constituency actually looks like. This is the show that started the conversation America is still not ready to finish.
Aug. 5, 2026

[HIATUS] The Cancer Mavericks EP1: The Big C Wasn’t Always on TV

[HIATUS] The Cancer Mavericks EP1: The Big C Wasn’t Always on TV

In 1971, President Richard Nixon signed the National Cancer Act, transforming cancer research with an unprecedented federal investment and launching what became known as the War on Cancer. The legislation did not emerge from scientific discovery alone. It was the culmination of decades of relentless advocacy by researchers, philanthropists, journalists, and patients who believed cancer demanded the same national commitment that had put astronauts on the Moon.


This episode traces the origins of the cancer survivorship movement by returning to a time when cancer was rarely discussed in public, many physicians withheld diagnoses from their patients, and surgery offered few lasting cures. It follows the pioneering work of pathologist Dr. Sidney Farber, whose early chemotherapy research challenged conventional thinking, and Mary Lasker, whose political strategy, fundraising, and public campaigns helped transform cancer from a private tragedy into a national public health priority. Together, they built the coalition that reshaped federal support for oncology research and forever changed the relationship between science, government, and the American public.


The story then turns to journalist and breast cancer survivor Rose Kushner, whose refusal to accept the standard one-step radical mastectomy challenged nearly a century of surgical dogma. Working alongside surgeon Dr. Bernard Fisher, Kushner helped bring evidence-based medicine to breast cancer treatment through randomized clinical trials that demonstrated less invasive surgery could achieve equivalent outcomes. Their efforts changed clinical practice, strengthened informed consent, and helped establish the principle that patients should participate in decisions about their own care.


The breakthroughs explored in this episode extended far beyond new treatments. They redefined the role of patients in medicine, accelerated clinical research, and laid the foundation for modern cancer survivorship. The movement that followed would not simply help more people live longer. It would change what surviving cancer meant.


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Like this episode? Rate and review The Cancer Mavericks: A History of Survivorship on your favorite podcast platform. For more information, visit CancerMavericks.com. Please send any questions to podcasts@matthewzachary.com.

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